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Article

Activating FGFR2-RAS-BRAF mutations in ameloblastoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2014

Brown Noah A, Rolland Delphine, McHugh Jonathan B, Weigelin Helmut C, Zhao Lili, Lim Megan S, Elenitoba-Johnson Kojo S J, Betz Bryan L

Abstract excerpt

PURPOSE: Ameloblastoma is an odontogenic neoplasm whose overall mutational landscape has not been well characterized. We sought to characterize pathogenic mutations in ameloblastoma and their clinical and functional significance with an emphasis on the mitogen-activated protein kinase (MAPK) pathway. EXPERIMENTAL DESIGN: A total of 84 ameloblastomas and 40 non-ameloblastoma odontogenic tumors were evaluated with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Jaw Neoplasms

Share to Mitogen-Activated Protein Kinases

Share to Proto-Oncogene Proteins B-raf

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Share to Receptor, Fibroblast Growth Factor, Type 2

Source

Identifiers

PMID: 24993163
DOI: 10.1158/1078-0432.CCR-14-1069

Genes

BRAF
FGFR2
CTNNB1
SMARCB1
SMO

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Activating FGFR2-RAS-BRAF mutations in ameloblastoma.PMID 24993163Read ↗

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