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Article

DNA methylation markers for oral pre-cancer progression: A critical review

17 Dec 2015

Abstract excerpt

Although oral cancers are generally preceded by a well-established pre-cancerous stage, there is a lack of well-defined clinical and morphological criteria to detect and signal progression from pre-cancer to malignant tumours. We conducted a critical review to summarize the evidence regarding aberrant DNA methylation patterns as a potential diagnostic biomarker predicting progression. We identified all relevant...

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PMID: 26690652
DOI: 10.1016/j.oraloncology.2015.11.012

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