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Mutational Landscape of Ameloblastoma: Analysis of BRAF and Other Key Mutations in Chinese Patients

3 Mar 2025

Abstract excerpt

OBJECTIVES: To investigate the prevalence of BRAF, SMO, KRAS, HRAS, NRAS, FGRF2, and CTNNB1 gene mutations in Chinese ameloblastoma (AM) patients and explore their associations with clinical characteristics. MATERIALS AND METHODS: DNA was extracted from 89 formalin-fixed paraffin-embedded AM samples (9 unicystic and 80 conventional). PCR and Sanger sequencing were used to detect mutations, followed by statistical...

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PMID: 40033546
DOI: 10.1111/odi.15286

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