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Enhancement of adalimumab expression in CHO cells by antioxidant small molecule additives and the underlying mechanism

2025-06-19

Abstract excerpt

<title>Abstract</title> <p><bold>Objective:</bold> Chinese hamster ovary (CHO) cells are widely used in the production of recombinant proteins and have become the main expression host for clinical therapeutic proteins. The method of using culture medium additives to effectively increase the yield of recombinant proteins. <bold>Results:</bold> 5 μM MYR, 25 μM DHM, 25 μM QUE, and 20 μM CUR can increase the expressi...

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Literature Corpus work
7e0b9703-8b46-5728-932e-a1d9d373a2c7
DOI
10.21203/rs.3.rs-6788918/v1
Open publication

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Enhancement of adalimumab expression in CHO cells by antioxidant small molecule additives and the underlying mechanismDOI 10.21203/rs.3.rs-6788918/v1
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