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A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis

2025-04-17

Abstract excerpt

<title>Abstract</title> <p>Hyperhomocysteinemia (HHy) can lead to vascular endothelial cell dysfunction, progressive inflammation and lipid metabolism disorder, which finally result in the onset and development of atherosclerosis, a major contributor to cardiovascular diseases. Given the complexity of pathological process, treatments based on a single target often showed limited therapeutic efficacy against AS. T...

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Literature Corpus work
c62c1dc6-c77e-5bf5-9891-ec20894b8d66
DOI
10.21203/rs.3.rs-5830667/v1
Open publication

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