Article

Invariants of Frameshifted Variants

2019-06-27

Abstract excerpt

Frameshifts in protein coding sequences are widely perceived as resulting in either non-functional or even deleterious protein products. Indeed, frameshifts typically lead to markedly altered protein sequences and premature stop codons. By analyzing complete proteomes from all three domains of life, we demonstrate that, in contrast, several key physicochemical properties of protein sequences exhibit significant ro...

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Identifiers and source

Literature Corpus work: 7e05c62f-253e-5c39-9100-2bb53a6bb182
DOI: 10.1101/684076

Open publication

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