Article

Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila.

2020-09-28

Abstract excerpt

<title>Abstract</title> <bold>Background </bold>Self-assembly of the amyloid-β (Aβ) peptide into aggregates, from small oligomers to amyloid fibrils, is fundamentally linked with Alzheimer’s disease (AD). However it is clear that not all forms of Aβ are equally harmful, and that linking a specific aggregate to toxicity also depends on the assays and model systems used [1, 2]. Though a central postulate of the...

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Literature Corpus work: 7dbb82a3-0b4a-5e82-8639-d115b9c98447
DOI: 10.21203/rs.3.rs-47473/v3

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