Article

Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder

2020-10-27

Abstract excerpt

<h4>Objectives</h4> To prioritize genes that are pleiotropically or potentially causally associated with the risk of MDD. <h4>Methods</h4> We applied the summary data-based Mendelian randomization (SMR) method integrating GWAS and expression quantitative trait loci (eQTL) data in 13 brain regions to identify genes that were pleiotropically associated with the risk of MDD. In addition, we repeated the analysis by u...

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Literature Corpus work: 7d8e3d45-1647-5586-ba6a-28f09334a4f9
DOI: 10.1101/2020.10.25.20219188

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