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Article

Peripheral PDCD4 Expression Links to T-Cell Immune Dysregulation in Major Depressive Disorder: Integrated Multi- Cohort Transcriptomic Analysis

2026-07-07

Abstract excerpt

<title>Abstract</title> <p>Background Programmed cell death 4 (PDCD4) is functionally linked to neuroinflammation and BDNF translation in the central nervous system, yet its peripheral expression landscape and relationship to immune dysregulation in major depressive disorder (MDD) remain unexplored. Methods This study integrated transcriptomic data from four GEO peripheral blood datasets (GSE98793, GSE39653, GS...

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Literature Corpus work
39e261da-b375-515d-af00-7adacc7a8989
DOI
10.21203/rs.3.rs-9993578/v1
Open publication

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Peripheral PDCD4 Expression Links to T-Cell Immune Dysregulation in Major Depressive Disorder: Integrated Multi- Cohort Transcriptomic AnalysisDOI 10.21203/rs.3.rs-9993578/v1
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