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Integrative systems neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder

2024-09-26

Abstract excerpt

<h4>ABSTRACT</h4> Major depressive disorder (MDD) is a complex psychiatric condition with a significant global impact. This study applied a genomic-driven integrative systems neuroimmunology approach to analyze transcriptomic data from 3,114 individuals (1,877 MDD patients and 1,237 controls). The analysis revealed neuroimmunological transcriptomic alterations, indicating cross-talk between the immune and nervous...

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Literature Corpus work
5579269b-f8b3-5c8b-bb50-4cf685c01eac
DOI
10.1101/2024.09.25.614771
Open publication

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Integrative systems neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorderDOI 10.1101/2024.09.25.614771
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