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Article

Transcriptome-wide association study identifies new susceptibility genes and pathways for depression.

Translational psychiatry - 21 May 2021

Li Xiaoyan, Su Xi, Liu Jiewei, Li Huijuan, Li Ming, Li Wenqiang, Luo Xiong-Jian

Abstract excerpt

Depression is the most prevalent mental disorder with substantial morbidity and mortality. Although genome-wide association studies (GWASs) have identified multiple risk variants for depression, due to the complicated gene regulatory mechanisms and complexity of linkage disequilibrium (LD), the biological mechanisms by which the risk variants exert their effects on depression remain largely unknown. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34021117
DOI: 10.1038/s41398-021-01411-w
PMCID: PMC8140098

Genes

FADS1
XPNPEP3
ZMAT2
ZNF501
ZNF502

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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