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Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitis

2024-10-09

Abstract excerpt

The intricate balance between the gut microbiome and host health inspires innovations in drug development. Commensal bacteria provide a multi-targeted approach ideal for treating complex medical conditions, like inflammatory bowel disease (IBD). These bacteria are self-replicating factories with broad targets that promote balanced intestinal inflammation, mucosal barrier function, and eubiosis. Yet, the lack of su...

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Identifiers and source

Literature Corpus work
7216559c-a83f-5910-a7e4-31c268a8f14f
DOI
10.1101/2024.10.08.617317
Open publication

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Bio-engineering a common probiotic to exploit colonic inflammation promotes reliable efficacy in translational models of colitisDOI 10.1101/2024.10.08.617317
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