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Model systems to study tumor-microbiome interactions in early-onset colorectal cancer

13 Feb 2025

Abstract excerpt

Colorectal cancer (CRC) is a major health problem, with an alarming increase of early-onset CRC (EO-CRC) cases among individuals under 50 years of age. This trend shows the urgent need for understanding the underlying mechanisms leading to EO-CRC development and progression. There is significant evidence that the gut microbiome acts as a key player in CRC by triggering molecular changes in the colon epithelium,...

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PMID: 39948421
DOI: 10.1038/s44321-025-00198-3

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