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Article

Circuit imaging biomarkers in preclinical and prodromal Parkinson's disease.

Molecular medicine (Cambridge, Mass.) - 16 Sept 2021

Meles Sanne K, Oertel Wolfgang H, Leenders Klaus L

Abstract excerpt

Parkinson's disease (PD) commences several years before the onset of motor features. Pathophysiological understanding of the pre-clinical or early prodromal stages of PD are essential for the development of new therapeutic strategies. Two categories of patients are ideal to study the early disease stages. Idiopathic rapid eye movement sleep behavior disorder (iRBD) represents a well-known prodromal stage of PD in...

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Identifiers

PMID: 34530732
DOI: 10.1186/s10020-021-00327-x
PMCID: PMC8447708

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