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More than <i>mcr</i> : Canonical Plasmid- and Transposon-Encoded Mobilized Colistin Resistance ( <i>mcr</i> ) Genes Represent a Subset of Phosphoethanolamine Transferases

2022-10-03

Abstract excerpt

Mobilized colistin resistance genes ( mcr ) may confer resistance to colistin, a last-resort, critically important antimicrobial for human health. mcr can often be transmitted horizontally (e.g., via mobile genetic elements); however, mcr encode phosphoethanolamine transferases (PET) closely related to chromosomally encoded, intrinsic lipid modification enzymes (e.g., EptA, EptB, CptA). To explore the genetic d...

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Literature Corpus work
7d7ae7be-9277-5c77-9393-bacbe6ad17f8
DOI
10.1101/2022.10.03.510586
Open publication

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