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EptA of Riemerella anatipestifer mediates phenotypes involved in colistin resistance and virulence.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2023

Chen Qiwei, Quan Heng, Yu Yongfeng, Liu Donghui, Li Caiyu, Chu Yuefeng, Gong Xiaowei

Abstract excerpt

Colistin (polymyxin E) is a group of cationic antimicrobial cyclic peptides and is recognized as a last-resort defense against lethal infections with carbapenem-resistant pathogens. In addition to the plasmid-borne mobilized phosphoethanolamine (PEA) transferases, the functional expression of lipid A-modifying enzymes encoded on chromosomes has been attributed to intrinsic bacterial colistin resistance. However,...

Topics

Escherichia coli
Phenotype
Transferases
Virulence
Colistin
Drug Resistance, Bacterial
Lipid A
Anti-Bacterial Agents
Riemerella

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37071453
DOI: 10.1096/fj.202300215R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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