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Identification of novel mobilized colistin resistance gene <i>mcr</i> -9 in a multidrug-resistant, colistin-susceptible <i>Salmonella enterica</i> serotype Typhimurium isolate using a combination of high-throughput, <i>in silico</i> screening and functional analysis

2019-02-03

Abstract excerpt

Mobilized colistin resistance ( mcr ) genes are plasmid-borne genes that confer resistance to colistin, an antibiotic used to treat severe bacterial infections. To date, eight known mcr homologues have been described ( mcr -1 to -8). Here, we describe mcr -9, a novel mcr homologue, detected in a Salmonella enterica serotype Typhimurium ( S. Typhimurium) genome using an in silico approach, followed by exper...

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Literature Corpus work
b23fde50-2c4c-59d2-be61-aa60b09cbb9f
DOI
10.1101/539361
Open publication

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Identification of novel mobilized colistin resistance gene <i>mcr</i> -9 in a multidrug-resistant, colistin-susceptible <i>Salmonella enterica</i> serotype Typhimurium isolate using a combination of high-throughput, <i>in silico</i> screening and functional analysisDOI 10.1101/539361
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