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Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments

23 Aug 2021

Abstract excerpt

Colistin is one of the last-line therapies against multidrug-resistant Gram-negative pathogens, especially carbapenemase-producing isolates, making resistance to this compound a major global public-health crisis. Until recently, colistin resistance in Gram-negative bacteria was known to arise only by chromosomal mutations. However, a plasmid-mediated colistin resistance mechanism was described in late 2015. This...

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PMID: 34438108
DOI: 10.1016/j.jgar.2021.07.021

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