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Massive analysis of 64’628 bacterial genomes to decipher a water reservoir and origin of mobile colistin resistance ( <i>mcr</i> ) gene variants: is there another role for this family of enzymes?

2019-09-10

Abstract excerpt

Since 2015, new worrying colistin resistance mechanism, mediated by mcr -1 gene has been reported worldwide along with eight newly described variants ( mcr -2 to mcr -9) but their source(s) and reservoir(s) remain largely unexplored. Here, we conducted a massive bioinformatic analysis of 64’628 downloaded bacterial genomes to investigate the reservoir and origin of these mcr variants. We identified a total of...

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Literature Corpus work
06b298fe-2356-5693-9117-f21967f7e836
DOI
10.1101/763474
Open publication

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Massive analysis of 64’628 bacterial genomes to decipher a water reservoir and origin of mobile colistin resistance ( <i>mcr</i> ) gene variants: is there another role for this family of enzymes?DOI 10.1101/763474
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