Deciphering MCR-2 Colistin Resistance

doi:10.1128/mbio.00625-17

Article

Deciphering MCR-2 Colistin Resistance

10 May 2017

Abstract excerpt

ABSTRACT Antibiotic resistance is a prevalent problem in public health worldwide. In general, the carbapenem β-lactam antibiotics are considered a final resort against lethal infections by multidrug-resistant bacteria. Colistin is a cationic polypeptide antibiotic and acts as the last line of defense for treatment of carbapenem-resistant bacteria. Very recently, a new plasmid-borne colistin resistance gene, mcr-2...

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