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Article

Colistin exposure enhances expression of eptB in colistin-resistant Escherichia coli co-harboring mcr-1

25 Jan 2022

Abstract excerpt

Colistin resistance has increased due to the increasing and inappropriate use of this antibiotic. The mechanism involves modification of lipid A with phosphoethanolamine (PEtN) and/or 4-amino-4deoxy-L-arabinose (L-Ara4N). EptA and eptB catalyze the transfer of phosphoethanolamine to lipid A. In this study, gene network was constructed to find the associated genes related to colistin resistance, and further in...

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PMID: 35079093
DOI: 10.1038/s41598-022-05435-0

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