Article

The <i>C. difficile clnRAB</i> operon initiates adaptations to the host environment in response to LL-37

2018-06-14

Abstract excerpt

<h4>ABSTRACT</h4> To cause disease, Clostridioides ( Clostridium ) difficile must resist killing by innate immune effectors in the intestine, including the host antimicrobial peptide, cathelicidin (LL-37). The mechanisms that enable C. difficile to adapt to the intestine in the presence of antimicrobial peptides are unknown. Expression analyses revealed an operon, CD630_16170-CD630_16190 ( clnRAB ), which i...

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Literature Corpus work: 7d76d62b-9615-5cb2-acee-26c1921350fe
DOI: 10.1101/347286

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