Article

Characterization of a β-lactamase that contributes to intrinsic β-lactam resistance in <i>Clostridioides difficile</i>

2019-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Clostrididioides difficile causes severe antibiotic-associated diarrhea and colitis. C. difficile is an anaerobic, Gram-positive spore former that is highly resistant to β-lactams, the most commonly prescribed antibiotics. The resistance of C. difficile to β-lactam antibiotics allows the pathogen to replicate and cause disease in antibiotic-treated patients. However, the mechanisms of β-lactam...

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Literature Corpus work: 498c1e56-4f2f-560c-ae17-01110af18190
DOI: 10.1101/630020

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