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Blood cultures contain populations of genetically diverse <i>Candida albicans</i> strains that may differ in echinocandin tolerance and virulence

2024-10-17

Abstract excerpt

It is unknown whether within-patient Candida albicans diversity is common during bloodstream infections (BSIs). We determined whole genome sequences of 10 C. albicans strains from blood cultures (BCs) in each of 4 patients. BCs in 3 patients contained mixed populations of strains that differed by large-scale genetic variants, including chromosome (Chr) 5 or 7 aneuploidy ( n =2) and Chr1 loss of heterozygosity (...

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Literature Corpus work
7d638330-ee29-55db-8900-80d6eec079c0
DOI
10.1101/2024.10.16.618724
Open publication

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Blood cultures contain populations of genetically diverse <i>Candida albicans</i> strains that may differ in echinocandin tolerance and virulenceDOI 10.1101/2024.10.16.618724
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