Article

A Global Analysis of Mutations Accompanying Microevolution in the Heterozygous Diploid Pathogen <i>Candida albicans</i>

2018-03-25

Abstract excerpt

Candida albicans is a heterozygous diploid yeast that is a commensal of the human gastrointestinal (GI) tract and a prevalent opportunistic pathogen. Here, whole-genome sequencing was performed on multiple C. albicans isolates passaged in different niches to characterize the complete spectrum of mutations arising during microevolution. We reveal that evolution during short time-scales (<600 generations) is driven...

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Literature Corpus work: e8a69075-8efb-5b81-ae10-4aee9a776823
DOI: 10.1101/288597

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