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Overlooked <i>Candida glabrata</i> petites are echinocandin tolerant, induce host inflammatory responses, and display poor <i>in vivo</i> fitness

2023-06-18

Abstract excerpt

Small colony variants (SCVs) are relatively common among some bacterial species and are associated with poor prognosis and recalcitrant infections. Similarly, Candida glabrata – a major intracellular fungal pathogen – produces small and slow-growing respiratory-deficient colonies, termed “petite.” Despite reports of clinical petite C . glabrata strains, our understanding of petite behavior in the host remains o...

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Literature Corpus work
e39daa5a-95ce-590c-9b00-4afbbc80f22f
DOI
10.1101/2023.06.15.545195
Open publication

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Overlooked <i>Candida glabrata</i> petites are echinocandin tolerant, induce host inflammatory responses, and display poor <i>in vivo</i> fitnessDOI 10.1101/2023.06.15.545195
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