Article

The Genome of the Human Pathogen <i>Candida albicans</i> is Shaped by Mutation and Cryptic Sexual Recombination

2018-04-28

Abstract excerpt

<h4>ABSTRACT</h4> The opportunistic fungal pathogen Candida albicans lacks a conventional sexual program and is thought to evolve, at least primarily, through the clonal acquisition of genetic changes. Here, we performed an analysis of heterozygous diploid genomes from 21 clinical isolates to determine the natural evolutionary processes acting on the C. albicans genome. Consistent with a model of inheritance by...

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Literature Corpus work: 3577a218-9999-572b-9704-047ace15466d
DOI: 10.1101/310201

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