Article
Genetic and phenotypic intra-species variation in Candida albicans.
Genome research - 1 Mar 2015
Hirakawa Matthew P, Martinez Diego A, Sakthikumar Sharadha, Anderson Matthew Z, Berlin Aaron, Gujja Sharvari, Zeng Qiandong, Zisson Ethan, Wang Joshua M, Greenberg Joshua M, Berman Judith, Bennett Richard J, Cuomo Christina A
Abstract excerpt
Candida albicans is a commensal fungus of the human gastrointestinal tract and a prevalent opportunistic pathogen. To examine diversity within this species, extensive genomic and phenotypic analyses were performed on 21 clinical C. albicans isolates. Genomic variation was evident in the form of polymorphisms, copy number variations, chromosomal inversions, subtelomeric hypervariation, loss of heterozygosity...
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