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[Pharmacogenomics of severe drug hypersensitivity reactions--from bench to bedside].

Przeglad lekarski - 1 Jan 2015

Porębski Grzegorz, Dyga Wojciech, Stobiecki Marcin, Czarnobilska Ewa

Abstract excerpt

Recent remarkable findings of pharmacogenomics and basic scientific research provided insights in the pathogenesis of severe drug hypersensitivity reactions such as drug rush with eosinophilia and systemic symptoms (DRESS), abacavir hypersensitivity syndrome or blistering reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis). There is increasing evidence for the strong associations of certain human...

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PMID: 27024960

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