Article

YAP orchestrates heterotypic endothelial cell communication via HGF/c-MET signaling in liver tumorigenesis

2020-03-18

Abstract excerpt

Next to cell autonomous mechanisms, the oncogene yes-associated protein (YAP) controls liver tumor initiation and progression via cell extrinsic functions creating a tumor-supporting environment. However, how YAP affects the microenvironment and in particular the vascular niche, which contributes to liver disease and hepatocarcinogenesis, is poorly understood. In this study, histo-morphological and molecular ch...

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Literature Corpus work: 7d5a50fa-d5c7-5189-93e0-8afd34993e8b
DOI: 10.1101/2020.03.17.995225

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