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Article

YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.

Cell cycle (Georgetown, Tex.) - 1 Jan 2024

Chen Haoyuan, Shang Yangyang, Li Xia, Wang Rongquan

Abstract excerpt

Yes-associated protein1 (YAP1), a downstream effector of the Hippo pathway, is over-expressed in several types of malignancies. We analyzed retrospectively the TCGA database using 447 colorectal cancer (CRC) samples to determine the correlation between YAP1 expression level and CRC patient prognosis. YAP1-enforced expressed CRC cell lines were constructed using the lentivirus particles containing a YAP1 insert....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38263746
DOI: 10.1080/15384101.2024.2309017
PMCID: PMC11005797

Genes

YAP1
AXL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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