Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emerging role of Hpo signaling and YAP in hepatocellular carcinoma

1 Jun 2015

Abstract excerpt

Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most common cause of cancer-related mortality worldwide. Due to the poor prognosis and limited therapeutic options, there is great interest in further understanding better the molecular underpinnings and potential molecular targets associated with HCC. The Hippo (Hpo) signaling pathway and YAP, its principal downstream effector,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Hippo pathway signaling and YAP/TAZ
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27508196
DOI: 10.2147/jhc.s48505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emerging role of Hpo signaling and YAP in hepatocellular carcinomaPMID 27508196Read ↗

Targeting YAP and Hippo signaling pathway in liver cancerSemantic proximity Read ↗

Complex roles of Hippo-YAP/TAZ signaling in hepatocellular carcinomaSemantic proximity Read ↗

Molecular Pathogenesis of Hepatocellular CarcinomaSemantic proximity Read ↗

Inactivation of Hippo Pathway Is Significantly Associated with Poor Prognosis in Hepatocellular CarcinomaSemantic proximity Read ↗

Molecular pathways in viral hepatitis-associated liver carcinogenesis: An updateSemantic proximity Read ↗

Genomics and Signaling Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

Emerging Signaling Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor RegressionSemantic proximity Read ↗

The role of the Hippo pathway in human disease and tumorigenesisSemantic proximity Read ↗

The pathogenesis of hepatocellular carcinoma.Semantic proximity Read ↗

Genetic and epigenetic aspects of initiation and progression of hepatocellular carcinomaSemantic proximity Read ↗

Molecular Targeted Therapy for Hepatocellular Carcinoma: Present Status and Future DirectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.