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Liver Tropism of Carcinoid Tumor Metastasis Driven by Developmental Overlaps Between SI-NECs and Hepatocytes: A Systematic Review Identifying Factors Governing Metastasis and Their Clinical Implications

2026-03-12

Abstract excerpt

<h4>Objective: </h4> This study aims to investigate how overlapping developmental transcription factors and signaling pathways between small intestinal neuroendocrine cells and hepatocytes govern liver-specific metastasis in carcinoid tumors, and to assess the clinical implications of these shared cell-type specific programs for early detection, risk-adapted surveillance, and targeted therapeutic strategies aimed...

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Literature Corpus work
832b2a5b-540d-5064-bdba-e15fa64e2d08
DOI
10.20944/preprints202603.0961.v1
Open publication

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Liver Tropism of Carcinoid Tumor Metastasis Driven by Developmental Overlaps Between SI-NECs and Hepatocytes: A Systematic Review Identifying Factors Governing Metastasis and Their Clinical ImplicationsDOI 10.20944/preprints202603.0961.v1
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