Article

Differential protective effects of typical versus atypical antipsychotic drugs in a phencyclidine microelectrode array model of schizophrenia

2024-09-16

Abstract excerpt

Abstract Phencyclidine (PCP), a non-competitive N-methyl-D-aspartate receptor antagonist, is known to produce schizophrenia-like psychosis in humans, including positive and negative symptoms as well as cognitive dysfunction. Moreover, acute administration of PCP can emulate corresponding behavioral symptoms in rodents. We investigated the effect of PCP and the possible rescuing potential of typical and atypical an...

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Literature Corpus work: 7d4bf7d5-6533-53b4-bd78-f85c221e8920
DOI: 10.22541/au.172646104.48099324/v1

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Differential protective effects of typical versus atypical antipsychotic drugs in a phencyclidine microelectrode array model of schizophreniaDOI 10.22541/au.172646104.48099324/v1Read

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