Article

Effects of NMDA antagonists on social behaviour: a systematic review and meta-analysis of preclinical studies

2026-05-15

Abstract excerpt

Social withdrawal is a key component of the negative symptom domain of schizophrenia, and pharmacological blockade of the N-methyl-D-aspartate receptor (NMDAR) is widely used to model schizophrenia-relevant phenotypes in animals. However, findings on social behaviour are inconsistent across paradigms and laboratories. We therefore conducted a systematic review and meta-analysis to synthesise the effects of dizocil...

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Literature Corpus work: b2684545-9038-5088-8201-665c5b79d2c6
DOI: 10.64898/2026.05.13.724847

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