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Towards a Personalized Medicine through Liquid Biopsy in Alzheimer’s disease: Epigenome of cell-free DNA reveals methylation differences linked to APOE status

2024-11-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Recent studies show that Alzheimer’s disease (AD) patients harbor specific methylation marks in the brain. However, accessing this epigenetic information “locked in the brain” while patients are alive is challenging. Liquid biopsy technique enables the study of circulating cell-free DNA (cfDNA) fragments originated from cells that have died and released their ge...

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Literature Corpus work: 7d17e247-0a66-5942-905b-7f4d13f52a1d
DOI: 10.21203/rs.3.rs-5358927/v1

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