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Article

The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.

Acta neuropathologica - 1 Oct 2016

Klein Hans-Ulrich, Bennett David A, De Jager Philip L

Abstract excerpt

The advent of new technologies and analytic approaches is beginning to provide an unprecedented look at features of the human genome that affect RNA expression. These "epigenomic" features are found in a number of different forms: they include DNA methylation, covalent modifications of histone proteins and non-coding RNAs. Some of these features have now been implicated in Alzheimer's disease (AD). Here, we focus...

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Identifiers

PMID: 27573688
DOI: 10.1007/s00401-016-1612-7
PMCID: PMC5189639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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