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Cell-free DNA methylation patterns in aging and their association with inflamm-aging

15 May 2024

Abstract excerpt

Aim: Liquid biopsies analyzing cell-free DNA (cfDNA) methylation in plasma offer a noninvasive diagnostic for diseases, with the potential of aging biomarkers underexplored. Methods: Utilizing enzymatic methyl-seq (EM-seq), this study assessed cfDNA methylation patterns in aging with blood from 35 healthy individuals. Results: It found aging signatures, including higher cfDNA levels and variations in fragment...

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PMID: 38869474
DOI: 10.1080/17501911.2024.2340958

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