Article

Aberrant Epigenetic Regulation in Head and Neck Cancer Due to Distinct EZH2 Overexpression and DNA Hypermethylation<strong> </strong>

2018-10-24

Abstract excerpt

EZH2 overexpression is associated with tumor proliferation, metastasis, and poor prognosis. Targeting and inhibiting EZH2 may be an effective therapeutic strategy for head and neck squamous cell carcinoma (HNSCC). We previously analyzed EZH2 mRNA expression in a well-characterized dataset of 230 (110 original and 120 validation cohorts) human head and neck cancer samples. This study aimed to investigate the effect...

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Literature Corpus work: 7ceef608-4ab9-5aa3-88a0-00a70691705d
DOI: 10.20944/preprints201810.0565.v1

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