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Article

EZH2-associated tumor malignancy: A prominent target for cancer treatment.

Clinical genetics - 1 Oct 2024

Sabour-Takanlou Maryam, Sabour-Takanlou Leila, Biray-Avci Cigir

Abstract excerpt

The discussion in this review centers around the significant relationships between EZH2 and the initiation, progression, metastasis, metabolism, drug resistance, and immune regulation of cancer. Polycomb group (PcG) proteins, which encompass two primary Polycomb repressor complexes (PRC1 and PRC2), have been categorized. PRC2 consists mainly of four subunits, namely EZH2, EED, SUZ12, and RbAp46/48. As the crucial...

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Share to Drug Resistance, Neoplasm
Share to Enhancer of Zeste Homolog 2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to PRC1 gene

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Source

Identifiers

PMID: 38881299
DOI: 10.1111/cge.14576

Genes

EED
PRC1
SUZ12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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