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A cilia-dependent inflammatory programme links bacterial detection to kidney disease

2026-04-28

Abstract excerpt

<h4>ABSTRACT</h4> The primary cilium is a microtubule-based sensory organelle projecting from the plasma membrane of most mammalian cells. Genetic defects in ciliary components cause chronic kidney disease (CKD) characterized by heightened production of inflammatory and fibrogenic mediators by tubular epithelial cells. Yet, whether this reflects a physiological role of the primary cilium remains unknown. Here, we...

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Literature Corpus work
5a497244-f037-5cfc-b771-42fcea4822ba
DOI
10.64898/2026.04.24.720658
Open publication

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