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A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury and matrix remodeling in patients with stone disease

2022-06-26

Abstract excerpt

Kidney stone disease causes significant morbidity and increases health care utilization. The pathogenesis of stone disease is not completely understood, due in part to the poor characterization of the cellular and molecular makeup of the kidney papilla and its alteration with disease. We deciphered the cellular and molecular niche of the human renal papilla in patients with calcium oxalate (CaOx) stone disease com...

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Literature Corpus work
f016b23c-5524-59c6-85a5-5013a96c4029
DOI
10.1101/2022.06.22.497218
Open publication

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A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury and matrix remodeling in patients with stone diseaseDOI 10.1101/2022.06.22.497218
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