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Article

Heritability and tissue specificity of expression quantitative trait loci.

PLoS genetics - 20 Oct 2006

Petretto Enrico, Mangion Jonathan, Dickens Nicholas J, Cook Stuart A, Kumaran Mande K, Lu Han, Fischer Judith, Maatz Henrike, Kren Vladimir, Pravenec Michal, Hubner Norbert, Aitman Timothy J

Abstract excerpt

Variation in gene expression is heritable and has been mapped to the genome in humans and model organisms as expression quantitative trait loci (eQTLs). We applied integrated genome-wide expression profiling and linkage analysis to the regulation of gene expression in fat, kidney, adrenal, and heart tissues using the BXH/HXB panel of rat recombinant inbred strains. Here, we report the influence of heritability...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17054398
DOI: 10.1371/journal.pgen.0020172
PMCID: PMC1617131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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