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Article

High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference in Bidirectionally Selected Rat Model.

PLoS genetics - 1 Aug 2016

Lo Chiao-Ling, Lossie Amy C, Liang Tiebing, Liu Yunlong, Xuei Xiaoling, Lumeng Lawrence, Zhou Feng C, Muir William M

Abstract excerpt

Investigations on the influence of nature vs. nurture on Alcoholism (Alcohol Use Disorder) in human have yet to provide a clear view on potential genomic etiologies. To address this issue, we sequenced a replicated animal model system bidirectionally-selected for alcohol preference (AP). This model is uniquely suited to map genetic effects with high reproducibility, and resolution. The origin of the rat lines (an...

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Identifiers

PMID: 27490364
DOI: 10.1371/journal.pgen.1006178
PMCID: PMC4973992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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