Article

Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells

2021-07-16

Abstract excerpt

<h4>ABSTRACT</h4> The capacity of humoral B cell-mediated immunity to effectively respond to and protect against pathogenic infections is largely driven by the presence of a diverse repertoire of polyclonal antibodies in the serum, which are produced by plasma cells (PCs). 1,2 Recent studies have started to reveal the balance between deterministic mechanisms and stochasticity of antibody repertoires on a genotyp...

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Literature Corpus work: 1b6eb707-82fe-50bf-a8f9-12a8bd8c6aad
DOI: 10.1101/2021.07.16.452687

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