Article

Novel Driver Mutations in GCB Lymphoma Patients That Affect Transcription Factors Binding

2025-03-17

Abstract excerpt

Mutations in the DNA can affect cancer development and progression not only by changing the amino acid chain but also by affecting different regulatory elements such as transcription factors. This study introduces a novel pipeline to identify “mutation blocks” - small genomic areas with high mutation rates that potentially influence transcription factors binding. By analyzing GCB lymphoma patient data, mutations b...

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Literature Corpus work: 7c6a6456-11ed-5fb9-921e-a35f9b5fe5e0
DOI: 10.1101/2025.03.15.643417

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