Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic landscape of mutations in Burkitt lymphoma.

Nature genetics - 1 Dec 2012

Love Cassandra, Sun Zhen, Jima Dereje, Li Guojie, Zhang Jenny, Miles Rodney, Richards Kristy L, Dunphy Cherie H, Choi William W L, Srivastava Gopesh, Lugar Patricia L, Rizzieri David A, Lagoo Anand S, Bernal-Mizrachi Leon, Mann Karen P, Flowers Christopher R, Naresh Kikkeri N, Evens Andrew M, Chadburn Amy, Gordon Leo I, Czader Magdalena B, Gill Javed I, Hsi Eric D, Greenough Adrienne, Moffitt Andrea B, McKinney Matthew, Banerjee Anjishnu, Grubor Vladimir, Levy Shawn, Dunson David B, Dave Sandeep S

Abstract excerpt

Burkitt lymphoma is characterized by deregulation of MYC, but the contribution of other genetic mutations to the disease is largely unknown. Here, we describe the first completely sequenced genome from a Burkitt lymphoma tumor and germline DNA from the same affected individual. We further sequenced the exomes of 59 Burkitt lymphoma tumors and compared them to sequenced exomes from 94 diffuse large B-cell lymphoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Burkitt Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Helicases

Share to Genes, myc

Share to GTP-Binding Protein alpha Subunits, G12-G13

Share to Lymphoma, Large B-Cell, Diffuse

Share to Multifunctional Enzymes

Share to Proto-Oncogene Proteins c-ret

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23143597
DOI: 10.1038/ng.2468
PMCID: PMC3674561

Genes

FTCD
GNA13
MYC
RET
SALL3
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic landscape of mutations in Burkitt lymphoma.PMID 23143597Read ↗

New clues to the molecular pathogenesis of Burkitt lymphoma revealed through next-generation sequencing.Semantic proximity Read ↗

The whole-genome landscape of Burkitt lymphoma subtypesSemantic proximity Read ↗

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.Semantic proximity Read ↗

Genetic heterogeneity of diffuse large B-cell lymphoma.Semantic proximity Read ↗

Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma.Semantic proximity Read ↗

Next generation sequencing and the management of diffuse large B-cell lymphoma: from whole exome analysis to targeted therapy.Semantic proximity Read ↗

Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphomaSemantic proximity Read ↗

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphomaSemantic proximity Read ↗

Mutational landscape of high-grade B-cell lymphoma with <i>MYC-, BCL2</i> and/or <i>BCL6</i> rearrangements characterized by whole-exome sequencingSemantic proximity Read ↗

Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes.Semantic proximity Read ↗

Analysis of CCND3 mutations in diffuse large B-cell lymphoma.Semantic proximity Read ↗

Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.