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Predicting regulatory mutations and their target genes by new computational integrative analysis: A study of follicular lymphoma.

Computers in biology and medicine - 1 Aug 2024

Wang Junbai, Yang Mingyi, Ali Omer, Dragland Jenny Sofie, Bjørås Magnar, Farkas Lorant

Abstract excerpt

Mutations in DNA regulatory regions are increasingly being recognized as important drivers of cancer and other complex diseases. These mutations can regulate gene expression by affecting DNA-protein binding and epigenetic profiles, such as DNA methylation in genome regulatory elements. However, identifying mutation hotspots associated with expression regulation and disease progression in non-coding DNA remains a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38901187
DOI: 10.1016/j.compbiomed.2024.108787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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