Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis

19 Nov 2018

Abstract excerpt

Abstract Circulating cell-free DNA (cfDNA) has received increasing interest as an apparent breakthrough approach in diagnostics, personalized medicine, and tumor biology. However, the structural features of cfDNA are poorly characterized. Specifically, the literature has discrepancies with regards to cfDNA size profile. We performed a blinded study of the distribution of cfDNA fragment sizes in cancer patient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Pancreatic and Hepatic Oncology Research
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30479833
DOI: 10.1038/s41525-018-0069-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysisPMID 30479833Read ↗

Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomicsSemantic proximity Read ↗

Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNASemantic proximity Read ↗

Refined characterization of circulating tumor DNA through biological feature integration.Semantic proximity Read ↗

Short single-stranded DNA with putative non-canonical structures comprises a novel class of plasma cell-free DNASemantic proximity Read ↗

Quantitative characterization of tumor cell-free DNA shortening.Semantic proximity Read ↗

Refined characterization of circulating tumor DNA through biological feature integrationSemantic proximity Read ↗

Detection of Circulating Tumor DNA in Plasma Using Targeted Sequencing.Semantic proximity Read ↗

Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNASemantic proximity Read ↗

Advantages of Single-Stranded DNA Over Double-Stranded DNA Library Preparation for Capturing Cell-Free Tumor DNA in Plasma.Semantic proximity Read ↗

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications.Semantic proximity Read ↗

Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing.Semantic proximity Read ↗

Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.