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Experimental Genetics Validation of <i>Plasmodium falciparum</i> Gametogenesis Essential Protein 1 (GEP1) as a Transmission Blocking Target

2025-05-29

Abstract excerpt

Transmission of Plasmodium parasites to the Anopheles vector critically depends on swift activation of mature gametocytes upon entry into the mosquito midgut. Induction of gametogenesis requires two simultaneous stimuli, a temperature drop and xanthurenic acid. Previous work in the murine malaria model Plasmodium yoelii identified a protein, termed gametogenesis essential protein ( GEP1 ), with a suggested rol...

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Literature Corpus work
7c4db7e8-87e2-5d44-834c-3afaf54804a3
DOI
10.1101/2025.05.28.656680
Open publication

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Experimental Genetics Validation of <i>Plasmodium falciparum</i> Gametogenesis Essential Protein 1 (GEP1) as a Transmission Blocking TargetDOI 10.1101/2025.05.28.656680
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